研究成果

科研项目

本科、博士毕业于东华大学bat365中文官方网站,2017年3月获得博士学位,2014-2016年在哈佛大学联合培养2年,2017-2021年在康奈尔大学从事博士后研究,2021年4月入职东华大学,担任教授、博士生导师,入选上海市领军人才(海外)、高等教育人才揽蓄行动A类(学科领军)、东华大学高层次海外引进人才。长期专注于纤维基生物医用材料的应用基础研究,包括人工胰腺治疗糖尿病等应用,主持国自然面上、国自然外国资深学者研究基金项目、国自然中白国际合作交流项目、国自然中韩国际合作交流项目、上海市细胞与基因治疗专项项目、学科创新领域培育等项目,总计经费600余万元,发表SCI论文34篇,被Nature, Science, Cell等高水平杂志引用3600余次,H因子21。其中,以第一作者或通讯作者发表SCI论文19篇,包括Advanced Materials, Advanced Functional Materials, Nano Letters, Nano Energy 等高影响力期刊,部分成果被Advanced Materials等期刊作为封面论文发表,4 篇一作SCI论文被引>200 次,3篇被引>400次,申请发明专利5项,起草行业标准2项。担任《Polymers》编委及客座主编,《Biofunctional Materials》副主编,《东华大学学报(自然科学版)》和《东华大学学报(英文版)》编委,《现代纺织技术》青年编委,捷克基金会评审专家,中国家用纺织品行业协会智库专家,曾担任全国功能材料与器件大会生物医用材料专题主席,受邀学术报告10余次,荣获中国纺织工业联合会科技进步奖二等奖、上海市优秀毕业生、王善元优秀博士论文等荣誉。

•国家自然科学基金面上项目,基于长期高效分子输运机制的三维人工胰腺构筑与应用,2023.1-2026.12,54万元,在研,主持。

•国家自然科学基金外国资深学者研究基金项目,光交联生物高分子和光聚合三维打印,2025.1-2026.12,160万元,主持

国家自然科学基金中白国际合作与交流项目,改性聚氨酯纳米纤维三维人工胰腺的研制及其长期抗纤维囊化机制,2024.1-2025.12,20万元,主持。

国家自然科学基金中韩国际合作与交流项目,水合作用调控纳米纤维增强果胶水凝胶人工胰腺的长期抗纤维囊化机制,2024.7-2026.6,15万元,主持。

上海市细胞与基因治疗专项项目,人类胰岛体外扩增技术的开发和迭代,2023.12-2026.11,150万元,在研,共主持。

上海市领军人才(海外),纤维基生物材料,2022.1-2024.12,75万,在研,主持。

东华大学高层次引进人才,高性能生物医用材料,2021.4-2024.3,150万元,在研,主持。

学科创新领域培育项目,纤维基三维人工胰腺的精准构筑及长期高效分子输运机制,2023.6-2026.5,50万元,在研,主持。

河南逸祥横向项目,卫生用品非织造材料关键技术及应用,2024.2-2026.1,50万元,在研,主持。

佛山必得福横向项目,纺熔医卫防护非织造材料关键制备技术及产业化,2021.9-2023.8,20万元,已结题,主持。

康奈尔大学-诺华诺德校企合作项目,纳米纤维免疫隔离人工胰腺的开发,2018.1-2021.6,3498万元,已结题,参与。

National Institute of Health (1 R01 DK105967-01A1),Engineering an Islet Thread from for type 1 diabetes,2018.7-2023.6.1221万元,在研,参与。

Juvenile Diabetes Research Foundation,Engineering A Highly Vascularized and Stackable Encapsulation Device,2017.9-2018.8,95万元,已结题,参与。

国家自然科学基金青年科学基金项目,51403033,表面具有取向沟槽结构的超细纤维制备及其对细胞生长作用的研究,2015-2017,25万元,已结题,参与。


代表论文

(#代表共同第一作者,*代表通讯作者)

1.W. Liu, J.A. Flanders, L.-H. Wang, Q. Liu, D.T. Bowers, K. Wang, A. Chiu, X. Wang, A.U. Ernst, K. Shariati, J.S. Caserto, B. Parker, D. Gao, M.D. Plesser, L.G. Grunnet, C. Rescan, R. Pimentel Carletto, L. Winkel, J.M. Melero-Martin, M. Ma*, A safe, fibrosis-mitigating, and scalable encapsulation device supports long-term function of insulin-producing cells.Small 18(8) (2022) 2104899(IF: 13.3, Citation 29).

2.W. Liu#, Y.S. Zhang#*, M.A. Heinrich#, F. De Ferrari, H.L. Jang, S.M. Bakht, M.M. Alvarez, J. Yang, Y.-C. Li, G. Trujillo-de Santiago, A.K. Miri, K. Zhu, P. Khoshakhlagh, G. Prakash, H. Cheng, X. Guan, Z. Zhong, J. Ju, G.H. Zhu, X. Jin, S.R. Shin, M.R. Dokmeci, A. Khademhosseini*, Rapid continuous multimaterial extrusion bioprinting. Advanced Materials 29(3) (2017) 1604630(IF: 29.4, Citation 435).

3.K. Shariati, A.S. Ling, S. Fuchs, B. Dillenburger, W. Liu*, M. Ma*, Hylozoic by design: converging material and biological complexities for cell-driven living materials with 4d behaviors,Advanced Functional Materials 32(7) (2022) 2108057 (IF: 19.0, Citation 14)

4.C. Fang, Y. Gu, H. Shi, J. Hu, Y. Wang, M. Pan, J. Feng, Y. Li, Y. Ma, T. Wang, Y. Wan, W. Liu, S.V. Kostjuk, M. Malkoch, W. Liu*, An autoclavable and transparent thermal cutter for reliably sealing wet nanofibrous membranes, Nano Letters (2024)(IF: 10.8)

5.M.A. Heinrich#, W. Liu#, A. Jimenez, J. Yang, A. Akpek, X. Liu, Q. Pi, X. Mu, N. Hu, R.M. Schiffelers, J. Prakash, J. Xie, Y.S. Zhang*, 3D bioprinting: from benches to translational applications. Small 15(23) (2019) (IF: 13.3, Citation 397).

6.Y. Wang, X. Zhang, X. Jin*, W. Liu*, An in situ self-charging triboelectric air filter with high removal efficiency, ultra-low pressure drop, superior filtration stability, and robust service life, Nano Energy 105 (2023) 108021(IF: 17.6, Citation 26).

7.D. Gao, A.U. Ernst, X. Wang, L. Wang, W. Liu*, M. Ma*, Engineering a hierarchical biphasic gel for subcutaneous vascularization, Advanced Healthcare Materials 11(19) (2022) 2200922(IF: 10.0, Citation 5).

8.W. Liu, M.A. Heinrich, Y. Zhou, A. Akpek, N. Hu, X. Liu, X. Guan, Z. Zhong, X. Jin, A. Khademhosseini*, Y.S. Zhang*, Extrusion bioprinting of shear-thinning gelatin methacryloyl bioinks, Advanced Healthcare Materials 6(12) (2017) 1601451 (IF: 10.0, Citation 459).

9.W. Liu, Z. Zhong, N. Hu, Y. Zhou, L. Maggio, A. Miri, A. Fragasso, X. Jin, A. Khademhosseini*, Y.S. Zhang*, Coaxial extrusion bioprinting of 3D microfibrous constructs with cell-favorable gelatin methacryloyl microenvironments, Biofabrication 10(2) (2018) 024102 (IF: 9.0, Citation 285).

10.X. Zhang, Y. Wang, W. Liu*, X. Jin*, Needle-punched electret air filters (NEAFs) with high filtration efficiency, low filtration resistance, and superior dust holding capacity, Separation And Purification Technology 282 (2022) 120146(IF: 8.6, Citation 27).

11.D. Gao, Y. Zhang, D.T. Bowers*, W. Liu*, M. Ma*, Functional hydrogels for diabetic wound management, APL Bioengineering 5(3) (2021) 031503(IF: 6.0, Citation 69).

12.X. Fan, X. Bai, L. Tan, C. Fang, X. Shen, H. Xu, Y. Wang, Y. Ma, Y. Li, X. Song, J. Hu, Y. Lu, X. Wei, J. Zhang, F. Li, Z. Zhu, S. Duan, Y. Zhou, H. Wu, W. Liu*, A transparent additive-free fibrous facial mask for skin moisturizing, Macromolecular Rapid Communications 44(17) (2023) 2300180(IF: 4.6, Citation 3).

13.H. Xu, S. Fang, L. Tan, Y. Li, Y. Wang, Y. Ma, X. Liu, B. Zaarour, W. Liu*, A comprehensive evaluation of the most-sold baby diapers on the market, Textile Research Journal (2024) 1-13(IF: 2.3, Citation 1).

14.X. Yuan, J. Zhang, J. Shi, W. Liu, A.S. Kritchenkov, S. Van Vlierberghe, L. Wang, W. Liu*, J. Gao*, Cotton fabric-reinforced hydrogels with excellent mechanical and broad-spectrum photothermal antibacterial properties, Polymers 16(10) (2024) 1346(IF: 5.0).

15.Q. Zhang, J. Chen, Z. He, W. Liu*, A.S. Kritchenkov, L. Wang, W. Liu*, J. Gao*, Fabrication of anti-fatigue double-wrapped yarns with excellent mechanical properties for generating compression fabrics, Polymers, 2024(IF: 5.0).

16.H. Li, W. Liu*, Z. Chen*, Effect of oligolactic acid stereocomplex microplates as rapid crystallization nucleating agents on the properties of poly(L-lactic acid), Polymer Engineering & Science 64(5) (2024) 1958-1970(IF: 3.2).

17.W. Liu#, L. Zhu#, C. Huang, X. Jin*, Direct electrospinning of ultrafine fibers with interconnected macropores enabled by in situ mixing microfluidics, ACS applied materials & interfaces 8(50) (2016) 34870-34878 (IF: 9.5, Citation 38).

18.W. Liu, C. Huang, X. Jin*, Electrospinning of grooved polystyrene fibers: effect of solvent systems, Nanoscale Research Letters 10(1) (2015) 237 (IF: 5.4, Citation 79).

19.W. Liu, C. Huang, X. Jin*, Tailoring the grooved texture of electrospun polystyrene nanofibers by controlling the solvent system and relative humidity, Nanoscale Research Letters 9(1) (2014) 350 (IF: 5.4, Citation 36).

其他论文

20.A.U. Ernst, L.-H. Wang*, S.C. Worland, B.A. Marfil-Garza, X. Wang, W. Liu, A. Chiu, T. Kin, D. O’Gorman, S. Steinschneider, A.K. Datta, K.K. Papas, A.M. James Shapiro, M. Ma*, A predictive computational platform for optimizing the design of bioartificial pancreas devices, Nature Communications 13(1) (2022) 6031(IF: 16.6, Citation 18).

21.Q. Liu, X. Wang, A. Chiu, W. Liu, S. Fuchs, B. Wang, L.-H. Wang, J. Flanders, Y. Zhang, K. Wang, J.M. Melero-Martin, M. Ma*, A zwitterionic polyurethane nanoporous device with low foreign-body response for islet encapsulation, Advanced Materials 33(39) (2021) 2102852(IF: 29.4, Citation 42).

22.Q. Liu, Y. Zhang, W. Liu, L.-H. Wang, Y.W. Choi, M. Fulton, S. Fuchs, K. Shariati, M. Qiao, V. Bernat, M. Ma*, A broad-spectrum antimicrobial and antiviral membrane inactivates sars-cov-2 in minutes, Advanced Functional Materials 31(47) (2021) 2103477(IF: 19.0, Citation 16).

23.L.-H. Wang, A.U. Ernst, J.A. Flanders, W. Liu, X. Wang, A.K. Datta, B. Epel, M. Kotecha, K.K. Papas, M. Ma*, An inverse-breathing encapsulation system for cell delivery, Science Advances 7(20) (2021) eabd5835(IF: 13.6, Citation 57).

24.X. Wang, G. Maxwell Kristina, K. Wang, T. Bowers Daniel, A. Flanders James, W. Liu, L.-H. Wang, Q. Liu, C. Liu, A. Naji, Y. Wang, B. Wang, J. Chen, U. Ernst Alexander, M. Melero-Martin Juan, R. Millman Jeffrey*, M. Ma*, A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes, Science Translational Medicine 13(596) (2021) eabb4601(IF: 17.1, Citation 91).

25.J. Chen, D. Wang, L.-H. Wang, W. Liu, A. Chiu, K. Shariati, Q. Liu, X. Wang, Z. Zhong, J. Webb, R.E. Schwartz, N. Bouklas, M. Ma*, An adhesive hydrogel with “load-sharing” effect as tissue bandages for drug and cell delivery, Advanced Materials 32(43) (2020) 2001628(IF: 29.4, Citation 145).

26.W. Jia, P.S. Gungor-Ozkerim, Y.S. Zhang*, K. Yue, K. Zhu, W. Liu, Q. Pi, B. Byambaa, M.R. Dokmeci, S.R. Shin*, A. Khademhosseini*, Direct 3D bioprinting of perfusable vascular constructs using a blend bioink, Biomaterials 106 (2016) 58-68(IF: 14.0, Citation 922).

27.C. Huang, Y. Ouyang*, H. Niu, N. He, Q. Ke, X. Jin, D. Li, J. Fang, W. Liu, C. Fan, T. Lin*, Nerve Guidance Conduits from Aligned Nanofibers: Improvement of Nerve Regeneration through Longitudinal Nanogrooves on a Fiber Surface, ACS applied materials & interfaces 7(13) (2015) 7189-7196(IF: 9.5, Citation 149).

28. M. Rocca, A. Fragasso, W. Liu, M.A. Heinrich, Y.S. Zhang*, Embedded multimaterial extrusion bioprinting, SLAS Technology 23(2) (2018) 154–163(IF: 2.7, Citation 108).


专利专著


1.Liu, W.; Ma, M.; Flanders, J. A.; Wang, L.; Bowers, D. T. ; Liu, Q., Nanofiber-enabled encapsulation devices and uses thereof (WO2021202945A1,排名:1/6)).

2.一种可灭菌的透明热切割封口器及其制备方法(申请号:202410502120.2,排名:1/2)

3.一种纤维间相互粘结的纺织材料及其制备方法(申请号:202411504210.7,排名:1/2)

4.一种径向异构聚丙烯长丝土工布及其制备方法 (申请号:202311574837.2,排名:6/8)

5.一种纳米碳酸钙压滤水处理方法 (申请号:202410402360.8,排名:3/4)

6.一种高效低阻的空气过滤材料 (ZL 2022 2 3201204.0,排名:3/11)

7.一种高效低阻复合过滤材料 (ZL 2022 2 3201332.5,排名:3/11)

8.FZ/T 93047-2023针刺机,排名9/18

9.FZ/T 93048.3-2023针刺机用针第三部分:锥形针,排名8/9




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